Glucosamine Complex & Chondroitin Sulfate - Featuring TruFlex

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When your joints call out for nourishment, give them the best money can buy with Swanson Glucosamine Complex & Chondroitin Sulfate. Each softgel supplies 400 mg of chondroitin sulfate with a 500 mg glucosamine complex including glucosamine sulfate and glucosamine HCl from with N-acetyl D-glucosamine. It's a great way to nourish the tissues that keep your joints working smoothly.

Glucosamine sulfate is the form that has been most extensively studied in clinical research for joint health. Glucosamine HCl provides a higher percentage of glucosamine by weight and is commonly used in combination formulas, and N-acetyl D-glucosamine (NAG) is a naturally occurring derivative of glucosamine that serves as a building block for glycosaminoglycans, compounds found in cartilage and other connective tissues.


Supplement Facts

Serving Size 1 Softgel

Servings Per Container 120

Amount Per Serving % Daily Value
Calories 10
Total Fat 0.5 g <1%
Glucosamine Complex (providing 412 mg glucosamine) 500 mg *
TruFlex® Glucosamine HCl (from shellfish) 475 mg *
TruFlex® Glucosamine Sulfate (2KCl) (from shellfish) 12.5 mg *
N-Acetyl D-Glucosamine 12.5 mg *
TruFlex® Chondroitin Sulfate USP 400 mg *

Percent Daily Values are based on a 2,000 calorie diet.
*Daily Value not established.

Other Ingredients: Soybean oil, softgel (gelatin, glycerin, purified water, carmel color), lecithin (soy), yellow beeswax.

Allergen Information: Contains shellfish (shrimp and crab) and soybeans.

Bioengineered Ingredients: Contains a bioengineered food ingredient.

Suggested Use: As a dietary supplement, take one softgel three times per day with food and water.

Warning: For adults only. Consult your healthcare provider before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Storage Instructions: Keep out of reach of children. Do not use if seal is broken. Store in a cool, dry place. Do not refrigerate.

Trademark Information: TruFlex® is a registered trademark of Swanson Health Products.




  1. What do glucosamine and chondroitin do?
    Glucosamine and chondroitin are naturally occurring compounds found in healthy cartilage. Glucosamine helps support the formation and maintenance of cartilage, while chondroitin helps retain water within cartilage to support its resilience and cushioning. Together, they help support joint health, flexibility, and comfortable movement.
  2. Why are glucosamine and chondroitin often taken together?
    Glucosamine and chondroitin work through complementary mechanisms to support joint health. Glucosamine helps maintain cartilage structure, while chondroitin helps support cartilage hydration and elasticity. Combining the two provides comprehensive nutritional support for healthy joints.
  3. Can I take glucosamine and chondroitin with other supplements?
    Yes. Glucosamine and chondroitin are commonly combined with ingredients such as MSM, collagen, hyaluronic acid, omega-3s, and turmeric because they support joint health through different mechanisms. If you are taking medications or have a medical condition, consult your healthcare provider before adding any new supplement to your routine.
  4. How long does it take to notice results from glucosamine and chondroitin?
    Joint health changes occur gradually, so glucosamine and chondroitin are intended for consistent, long-term use. Individual responses vary, but many people use these supplements daily for several weeks before noticing benefits. For best results, take the product as directed.
  5. What makes Swanson Glucosamine Complex & Chondroitin Sulfate unique?
    Swanson Glucosamine Complex & Chondroitin Sulfate combines three forms of glucosamine—glucosamine HCl, glucosamine sulfate, and N-acetyl D-glucosamine—with 400 mg of chondroitin sulfate in each softgel. Unlike formulas that provide a single form of glucosamine, this comprehensive blend delivers multiple cartilage-supporting compounds that work together to help maintain joint integrity, flexibility, movement, and healthy cartilage in a convenient softgel.
  6. Is Swanson Glucosamine Complex & Chondroitin Sulfate suitable for special diets?
    Swanson Glucosamine Complex & Chondroitin Sulfate is dairy free. However, it is not gluten free, non-GMO, or suitable for vegan or vegetarian diets because it contains shellfish-derived glucosamine and chondroitin, and a gelatin softgel. Always review the product label for the most current ingredient and allergen information.